Cancers can develop through epigenetic pathways even without driver gene mutations (DGMs), according to a study from Science Tokyo. Researchers uncovered the YAP1–TEAD–TET1 axis, which triggers DNA demethylation and activates multiple oncogenes in hepatocellular carcinoma. Suppressing TET1 reduced tumor formation in mice, while analysis of human liver disease data supported the relevance of these findings. This study reveals an alternative epigenetic route to cancer development and offers new insights into DGM-negative cancers.
🛡️
Just a quick checkWe’re checking your connection to prevent automated abuse
| # | Наименование новости | Тональность | Информативность | Дата публикации |
|---|---|---|---|---|
| 1 | This unusual epigenetic modifier promotes certain cancers but suppresses others | 0 | 7 | 10-07-2026 |
| 2 | Mayo Clinic discovers rare gene mutation that causes fatty liver disease | 0 | 7.1 | 07-03-2026 |
| 3 | Российские ученые выявили белки-маркеры для ранней диагностики болезней печени | 0 | 11.41 | 19-08-2026 |
| 4 | Takeaways and beers: Experts discover the lifestyle choices that trigger most dangerous form of bowel cancer | 0 | 7 | 03-07-2026 |
| 5 | New AI tool assesses liver cancer treatment success | 0 | 21.11 | 15-10-2026 |
| 6 | Scientists just mapped the mutations that power cancer growth | 0 | 6.9 | 05-02-2026 |
| 7 | Ученые выяснили, как сигареты и алкоголь «переписывают» ДНК и запускают рак | 0 | 7.51 | 31-07-2026 |
| 8 | Российские ученые выявили новые мутации, которые провоцируют опухоли поджелудочной железы | 0 | 0 | 30-09-2019 |
| 9 | Ученые раскрыли неожиданную причину возникновения рака | 0 | 5 | 04-07-2026 |